Title : [Urinary S100B protein and lactate/creatinine ratio measurements: a tool for the early identification of neonatal hypoxic-ischemic encephalopathy].

Pub. Date : 2005 Aug

PMID : 16191261






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 (2) A significantly positive correlation was found between the level of urinary S100B protein within three days and the urinary lactate/creatinine ratio within the first day and between the level of urinary S100B protein within three days and clinical degree (P < 0.05). Lactic Acid S100 calcium binding protein B Homo sapiens
2 (3) When S100B concentration was 0.47 microg/L and urinary lactate/creatinine ratio was 0.55, the sensitivity and specificity of detecting the third day urinary S100B alone, were respectively 90.4%, 91.9%. Lactic Acid S100 calcium binding protein B Homo sapiens
3 CONCLUSION: On the basis of clinical manifestations of asphyxic neonatals, detecting the level of urinary S100B within three days and the first day urinary lactate/creatinine ratio may be of important value in early diagnosis and grading of HIE. Lactic Acid S100 calcium binding protein B Homo sapiens