Title : Structure of human phytanoyl-CoA 2-hydroxylase identifies molecular mechanisms of Refsum disease.

Pub. Date : 2005 Dec 9

PMID : 16186124






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Like other 2OG oxygenases, PAHX possesses a double-stranded beta-helix core, which supports three iron binding ligands (His(175), Asp(177), and His(264)); the 2-oxoacid group of 2OG binds to the Fe(II) in a bidentate manner. Iron phytanoyl-CoA 2-hydroxylase Homo sapiens