Title : Phorbol ester-induced apoptosis in prostate cancer cells via autocrine activation of the extrinsic apoptotic cascade: a key role for protein kinase C delta.

Pub. Date : 2005 Nov 25

PMID : 16183650






1 Functional Relationships(s)
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1 The apoptotic effect of phorbol 12-myristate 13-acetate in LNCaP cells was impaired by inhibition or depletion of tumor necrosis factor alpha-converting enzyme, the enzyme responsible for tumor necrosis factor alpha (TNFalpha) shedding. Tetradecanoylphorbol Acetate ADAM metallopeptidase domain 17 Homo sapiens