Pub. Date : 2005 Oct
PMID : 16164642
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | VEGF-induced eNOS phosphorylation was abolished by SU1498, a VEGF-R2 inhibitor, LY294002, a PI3K inhibitor, and infection of cells with an adenovirus carrying a dominant negative-mutant of Akt, demonstrating the requirement of the VEGF-R2/IRS-1/PI3K/Akt axis for activation of eNOS. | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one | vascular endothelial growth factor A | Homo sapiens |
| 2 | ERK phosphorylation was abolished by LY294002, suggesting ERK was downstream of PI3K in VEGF-treated GENC. | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one | vascular endothelial growth factor A | Homo sapiens |