Title : Anthracyclines, proteasome activity and multi-drug-resistance.

Pub. Date : 2005 Sep 13

PMID : 16159384






1 Functional Relationships(s)
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1 Observations that cyclosporin A, and certain other substances, inhibit both the proteasome and P-glycoprotein led us to investigate whether anthracyclines, well known substrates of P-gp, also inhibit the function of the proteasome. Anthracyclines phosphoglycolate phosphatase Homo sapiens