Title : Indole-3-carbinol activates the ATM signaling pathway independent of DNA damage to stabilize p53 and induce G1 arrest of human mammary epithelial cells.

Pub. Date : 2006 Feb 15

PMID : 16152627






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The p53-MDM2 interaction and absence of p21 production were restored in cells treated with I3C and the ATM inhibitor wortmannin. Wortmannin tumor protein p53 Homo sapiens