Pub. Date : 2005
PMID : 16131811
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | C-reactive protein induces NF-kappaB activation through intracellular calcium and ROS in human mesangial cells. | Reactive Oxygen Species | C-reactive protein | Homo sapiens |
| 2 | Both intracellular calcium and ROS was induced by CRP. | Reactive Oxygen Species | C-reactive protein | Homo sapiens |
| 3 | CONCLUSION: CRP exerted a proinflammatory effect in human mesangial cells by inducing MCP-1 gene expression via NF-kappaB activation, which was mediated, at least in part, through intracellular calcium and ROS. | Reactive Oxygen Species | C-reactive protein | Homo sapiens |