Title : Synthesis of glycoconjugate vaccines for Candida albicans using novel linker methodology.

Pub. Date : 2005 Sep 2

PMID : 16122263






1 Functional Relationships(s)
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1 Here, we report the gram-scale syntheses of both types of epitopes by an approach that utilizes glucosyl trichloroacetimidate donor 2 to first create a beta-glucopyranoside linkage and then epimerizes the C-2 center via an oxidation-reduction sequence that provides an efficient multigram scale route to the beta-mannopyranosides 5, 8, and 15. trichloroacetamide complement C2 Homo sapiens