Title : 2-bromoethylamine, a suicide inhibitor of semicarbazide-sensitive amine oxidase, increases hydralazine hypotension in rats.

Pub. Date : 2005 Sep

PMID : 16116337






4 Functional Relationships(s)
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1 Previous work has shown that inhibitors of the predominantly vascular enzyme semicarbazide-sensitive amine oxidase (SSAO) potentiate the hypotensive response to hydralazine, itself a SSAO inhibitor, in anesthetized rats. Hydralazine amine oxidase, copper containing 3 Rattus norvegicus
2 Previous work has shown that inhibitors of the predominantly vascular enzyme semicarbazide-sensitive amine oxidase (SSAO) potentiate the hypotensive response to hydralazine, itself a SSAO inhibitor, in anesthetized rats. Hydralazine amine oxidase, copper containing 3 Rattus norvegicus
3 Previous work has shown that inhibitors of the predominantly vascular enzyme semicarbazide-sensitive amine oxidase (SSAO) potentiate the hypotensive response to hydralazine, itself a SSAO inhibitor, in anesthetized rats. Hydralazine amine oxidase, copper containing 3 Rattus norvegicus
4 The charactertistics of hydralazine potentiation by bromoethylamine were considered compatible with the mechanism of SSAO inhibition by the amine. Hydralazine amine oxidase, copper containing 3 Rattus norvegicus