Pub. Date : 2005 Aug 25
PMID : 16107155
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | (-)-Lobeline (2R,6S,10S), an antagonist at nicotinic acetylcholine receptors (nAChRs), inhibits the neurochemical and behavioral effects of methamphetamine and inhibits dopamine transporter (DAT) and vesicular monoamine transporter (VMAT2) function. | Lobeline | solute carrier family 18 member A2 | Homo sapiens |
| 2 | Generally, all of these analogues had lower affinities at alpha4beta2 and alpha7 nAChRs compared to lobeline, thereby increasing selectivity for VMAT2. | Lobeline | solute carrier family 18 member A2 | Homo sapiens |