Title : Treatment of vascular smooth muscle cells with estradiol and beta-adrenergic agonists has an additive effect on cAMP levels, but no additive effect on inhibition of collagen synthesis.

Pub. Date : 2005 Aug

PMID : 16102256






2 Functional Relationships(s)
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1 When VSMCs were treated with both oestrogen and isoproterenol there was an additive effect on cellular cAMP levels although the observed decrease in collagen synthetic rates was the same as observed in cells treated with just oestrogen. Isoproterenol cathelicidin antimicrobial peptide Homo sapiens
2 Treatment of VSMCs with propranolol inhibited isoproterenol-induced changes in cAMP but had no effect on either oestrogen-induced increases in cAMP levels or inhibition of collagen synthesis. Isoproterenol cathelicidin antimicrobial peptide Homo sapiens