Title : Caffeic acid phenethyl ester (CAPE) prevents transformation of human cells by arsenite (As) and suppresses growth of As-transformed cells.

Pub. Date : 2005 Sep 15

PMID : 16085347






1 Functional Relationships(s)
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1 Co-incubation of N-HOS with As and CAPE (0.5-2.5 microM) prevented As-mediated declines in cytokine mRNAs in the co-treated cells, as well as their transformation to anchorage independence, while it caused decreases in c-jun mRNA. arsenite Jun proto-oncogene, AP-1 transcription factor subunit Homo sapiens