Title : Dual activators of the sterol biosynthetic pathway of Saccharomyces cerevisiae: similar activation/regulatory domains but different response mechanisms.

Pub. Date : 2005 Aug

PMID : 16055745






3 Functional Relationships(s)
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1 We have identified the transcriptional activation domains of Upc2p and Ecm22p and found that UPC2-1, a mutation that allows cells to take up sterols aerobically, increased the potency of the activation domain. Sterols Upc2p Saccharomyces cerevisiae S288C
2 We have identified the transcriptional activation domains of Upc2p and Ecm22p and found that UPC2-1, a mutation that allows cells to take up sterols aerobically, increased the potency of the activation domain. Sterols Upc2p Saccharomyces cerevisiae S288C
3 The C-terminal regions of Upc2p and Ecm22p, which contained activation domains, also conferred regulation in response to sterol levels. Sterols Upc2p Saccharomyces cerevisiae S288C