Title : Structure-activity relationships for the action of 11 pyrethroid insecticides on rat Na v 1.8 sodium channels expressed in Xenopus oocytes.

Pub. Date : 2006 Mar 15

PMID : 16051293






1 Functional Relationships(s)
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1 Modification of Na v 1.8 sodium channels by cyfluthrin, cyhalothrin, cypermethrin and deltamethrin was enhanced 2.3- to 3.4-fold by repetitive stimulation; this effect appeared to result from the accumulation of persistently open channels rather than preferential binding to open channel states. decamethrin sodium voltage-gated channel alpha subunit 10 Rattus norvegicus