Title : Docosahexaenoic acid: a positive modulator of Akt signaling in neuronal survival.

Pub. Date : 2005 Aug 2

PMID : 16040805






4 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Docosahexaenoic acid: a positive modulator of Akt signaling in neuronal survival. Docosahexaenoic Acids AKT serine/threonine kinase 1 Homo sapiens
2 Docosahexaenoic acid (DHA), an n-3 polyunsaturated fatty acid highly enriched in neuronal membranes, promotes neuronal survival by facilitating membrane translocation/activation of Akt through its capacity to increase phosphatidylserine (PS), the major acidic phospholipid in cell membranes. Docosahexaenoic Acids AKT serine/threonine kinase 1 Homo sapiens
3 Docosahexaenoic acid (DHA), an n-3 polyunsaturated fatty acid highly enriched in neuronal membranes, promotes neuronal survival by facilitating membrane translocation/activation of Akt through its capacity to increase phosphatidylserine (PS), the major acidic phospholipid in cell membranes. Docosahexaenoic Acids AKT serine/threonine kinase 1 Homo sapiens
4 The activation of PI (3)K and phosphatidylsinositol triphosphate formation were not affected by DHA, indicating that membrane interaction of Akt is the event responsible for the DHA effect. Docosahexaenoic Acids AKT serine/threonine kinase 1 Homo sapiens