Pub. Date : 2005 Aug
PMID : 16040657
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | CYP51 exists in all organisms that synthesize sterols de novo. | Sterols | CYTOCHROME P450 51G1 | Arabidopsis thaliana |
| 2 | Measurements of endogenous sterol levels in the cyp51A2 mutant revealed that it accumulates obtusifoliol, the substrate of CYP51, and a high proportion of 14alpha-methyl-delta8-sterols, at the expense of campesterol and sitosterol. | Sterols | CYTOCHROME P450 51G1 | Arabidopsis thaliana |
| 3 | Measurements of endogenous sterol levels in the cyp51A2 mutant revealed that it accumulates obtusifoliol, the substrate of CYP51, and a high proportion of 14alpha-methyl-delta8-sterols, at the expense of campesterol and sitosterol. | Sterols | CYTOCHROME P450 51G1 | Arabidopsis thaliana |
| 4 | Taken together, our results demonstrate that the Arabidopsis CYP51A2 gene encodes a functional obtusifoliol 14alpha-demethylase enzyme and plays an essential role in controlling plant growth and development by a sterol-specific pathway. | Sterols | CYTOCHROME P450 51G1 | Arabidopsis thaliana |