Title : Synergistic enhancement of Toll-like receptor responses by NOD1 activation.

Pub. Date : 2005 Aug

PMID : 16021603






1 Functional Relationships(s)
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1 NOD1 activation by low nanomolar concentrations of the specific muropeptide ligand M-TriDAP induced minimal human peripheral blood mononuclear cell TNF-alpha, IL-1beta or IL-10 secretion, but synergistically increased Toll-like receptor (TLR)-induced responses. L-Ala-gamma-D-Glu-meso-diaminopimelic acid interleukin 1 beta Homo sapiens