Title : Activation of small GTPase Ras and renal fibrosis.

Pub. Date : 2005 May-Jun

PMID : 16013027






1 Functional Relationships(s)
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1 Mesangial cell proliferation induced by high glucose can be reverted by 3-hydroxy-3-methylglutaryl CoA reductase inhibitor which blocks the synthesis of prenyl groups and consequently Ras activation. Glucose 3-hydroxy-3-methylglutaryl-CoA reductase Homo sapiens