Title : The characterization of a novel rigid nicotine analog with alpha7-selective nAChR agonist activity and modulation of agonist properties by boron inclusion.

Pub. Date : 2005 Sep 1

PMID : 16005216






2 Functional Relationships(s)
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1 The characterization of a novel rigid nicotine analog with alpha7-selective nAChR agonist activity and modulation of agonist properties by boron inclusion. Nicotine cholinergic receptor nicotinic beta 1 subunit Rattus norvegicus
2 Similar N-conjugation of S(-)nicotine with cyanoborane decreased efficacy for alpha3beta4 and alpha4beta2 receptors, as well as for alpha7 nAChR. Nicotine cholinergic receptor nicotinic beta 1 subunit Rattus norvegicus