Title : Modulation of cytochrome P450 enzymes by organosulfur compounds from garlic.

Pub. Date : 2005 Dec

PMID : 16000231






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Gastric intubation of rats with a single dose of 200 mg/kg diallyl sulfide (DAS), diallyl disulfide (DADS), and allyl methyl sulfide (AMS) decreased hepatic CYP2E1 protein by 45%, 25% and 47%, respectively, and this inhibition was sustained after 1, 4 and 8 weeks of treatment by these compounds. allyl sulfide cytochrome P450, family 2, subfamily e, polypeptide 1 Rattus norvegicus
2 Gastric intubation of rats with a single dose of 200 mg/kg diallyl sulfide (DAS), diallyl disulfide (DADS), and allyl methyl sulfide (AMS) decreased hepatic CYP2E1 protein by 45%, 25% and 47%, respectively, and this inhibition was sustained after 1, 4 and 8 weeks of treatment by these compounds. allyl sulfide cytochrome P450, family 2, subfamily e, polypeptide 1 Rattus norvegicus