Title : Cooperative function of rho GDS and rho GDI to regulate rho p21 activation in smooth muscle.

Pub. Date : 1992 May 29

PMID : 1599487






4 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The GDP/GTP exchange reaction of rho p21, a member of ras p21-related small GTP-binding protein superfamily, is regulated by two stimulatory GDP/GTP exchange proteins (GEPs), named smg GDS and rho GDS, and by one inhibitory GEP, named rho GDI. Guanosine Diphosphate ras homolog family member A Bos taurus
2 The GDP/GTP exchange reaction of rho p21, a member of ras p21-related small GTP-binding protein superfamily, is regulated by two stimulatory GDP/GTP exchange proteins (GEPs), named smg GDS and rho GDS, and by one inhibitory GEP, named rho GDI. Guanosine Diphosphate ras homolog family member A Bos taurus
3 In bovine aortic smooth muscle, rho GDS and rho GDI were major GEPs for rho p21, and the rho GDI activity on the GDP/GTP exchange reaction of rho p21 was stronger than the rho GDS activity in their simultaneous presence. Guanosine Diphosphate ras homolog family member A Bos taurus
4 Moreover, in the crude cytosol, the GDP-bound form of rho p21 was complexed with rho GDI but not with rho GDS. Guanosine Diphosphate ras homolog family member A Bos taurus