Title : Renal and hepatic accumulation of cadmium and lead in the expression of CYP4F2 and CYP2E1.

Pub. Date : 2005 Nov 15

PMID : 15994032






2 Functional Relationships(s)
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1 These findings suggest that Cd may be an inducer of renal CYP4F2 and hepatic CYP2E1 and that increased renal CYP4F2 expression may implicate in Cd-linked renal tubular dysfunction and high blood pressure, involving CYP4F2-dependent arachidonic acid metabolism. Arachidonic Acid cytochrome P450 family 4 subfamily F member 2 Homo sapiens
2 These findings suggest that Cd may be an inducer of renal CYP4F2 and hepatic CYP2E1 and that increased renal CYP4F2 expression may implicate in Cd-linked renal tubular dysfunction and high blood pressure, involving CYP4F2-dependent arachidonic acid metabolism. Arachidonic Acid cytochrome P450 family 4 subfamily F member 2 Homo sapiens