Pub. Date : 2005
PMID : 15987423
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Cytochrome P450 2D6 (CYP2D6) and sulfotransferase 1A1 (SULT1A1) are polymorphic and are involved in the metabolism of tamoxifen. | Tamoxifen | sulfotransferase family 1A member 1 | Homo sapiens |
| 2 | Cytochrome P450 2D6 (CYP2D6) and sulfotransferase 1A1 (SULT1A1) are polymorphic and are involved in the metabolism of tamoxifen. | Tamoxifen | sulfotransferase family 1A member 1 | Homo sapiens |
| 3 | The combination of CYP2D6*4 and/or SULT1A1*1/*1 genotypes comprised 60% of the patients and showed a 62% decreased risk of distant recurrence with tamoxifen (relative risk = 0.38, 95% confidence interval = 0.19-0.74, P = 0.0041). | Tamoxifen | sulfotransferase family 1A member 1 | Homo sapiens |