Title : Effect of efavirenz on the pharmacokinetics of simvastatin, atorvastatin, and pravastatin: results of AIDS Clinical Trials Group 5108 Study.

Pub. Date : 2005 Jul 1

PMID : 15980690






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 EFV is a mixed inducer/inhibitor of cytochrome P450 (CYP) 3A4 isozyme and may interact with hydroxymethylglutaryl coenzyme A (HMG-CoA) reductase inhibitors that are primarily metabolized via CYP3A4. efavirenz 3-hydroxy-3-methylglutaryl-CoA reductase Homo sapiens