Title : Analysis of pathological defects in methionine metabolism using a simple mathematical model.

Pub. Date : 2005 Sep 25

PMID : 15963701






2 Functional Relationships(s)
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1 Application of the characteristics of transformed hepatocytes to our model, i.e., substitution of the MAT I/III isozyme by MAT II, loss of GNMT activity and activation of polyamine biosynthesis, leads to the prediction of a significantly different dependence of methionine metabolism on methionine concentrations. Methionine methionine adenosyltransferase 2B Homo sapiens
2 Application of the characteristics of transformed hepatocytes to our model, i.e., substitution of the MAT I/III isozyme by MAT II, loss of GNMT activity and activation of polyamine biosynthesis, leads to the prediction of a significantly different dependence of methionine metabolism on methionine concentrations. Methionine methionine adenosyltransferase 2B Homo sapiens