Pub. Date : 2005 Jul
PMID : 15944764
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The purposes of this study were to evaluate the antitumor activity of S-1 (1 M tegafur, 0.4 M 5-chloro-2,4-dihydroxypyridine and 1 M potassium oxonate) on human lung tumor xenografts, as compared with other fluoro-pyrimidines, and to investigate the relationships between fluoropyrimidine antitumor activities and four distinct enzymatic activities involved in the phosphorylation and degradation pathways of 5-fluorouracil (5-FU) metabolism. | Tegafur | proteasome 26S subunit, non-ATPase 1 | Homo sapiens |
2 | Cluster analysis, on the basis of antitumor activity, indicated that S-1/UFT and 5"-DFUR/capecitabine/5-FU could be classified into another group. | Tegafur | proteasome 26S subunit, non-ATPase 1 | Homo sapiens |