Title : A novel therapeutic strategy for medullary thyroid cancer based on radioiodine therapy following tissue-specific sodium iodide symporter gene expression.

Pub. Date : 2005 Aug

PMID : 15941870






1 Functional Relationships(s)
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1 RESULTS: hNIS-transfected TT cells showed perchlorate-sensitive iodide uptake, accumulating 125-I about 12-fold in vitro with organification of 4% of accumulated iodide resulting in a significant decrease in iodide efflux. sensitive iodide solute carrier family 5 member 5 Homo sapiens