Pub. Date : 2005 Aug
PMID : 15941855
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Polyamine depletion reduces TNFalpha/MG132-induced apoptosis in bone marrow stromal cells. | Polyamines | tumor necrosis factor | Homo sapiens |
| 2 | The effect of DFMO on TNFalpha/MG132-induced upregulation of caspase-3 activity was reversed by the addition of 100 microM putrescine, confirming that polyamines were really involved in the apoptotic process. | Polyamines | tumor necrosis factor | Homo sapiens |
| 3 | Also, the number of apoptotic BMSCs after TNFalpha/MG132 treatment, as determined by terminal transferase-mediated dUTP nick end-labeling (TUNEL) assay, were threefold reduced after polyamine depletion (p<.05). | Polyamines | tumor necrosis factor | Homo sapiens |