Title : The NR3B subunit does not alter the anesthetic sensitivities of recombinant N-methyl-D-aspartate receptors.

Pub. Date : 2005 Jun

PMID : 15920196






1 Functional Relationships(s)
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1 Mutations of two amino acid residues in the NR3B subunit at positions homologous to the N and N + 1 sites in the NR1 and NR2 subunits, which constitute the blocking sites for Mg2+ and ketamine, did not affect the sensitivities of NR1/NR2B/NR3B channels to Mg2+, ketamine and isoflurane. Ketamine glutamate ionotropic receptor NMDA type subunit 1 L homeolog Xenopus laevis