Title : Uncovering the molecular mode of action of the antimalarial drug atovaquone using a bacterial system.

Pub. Date : 2005 Jul 22

PMID : 15917236






1 Functional Relationships(s)
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1 Here, we show that atovaquone blocks this domain movement by locking the iron-sulfur subunit in its cytochrome b-binding conformation. Iron mitochondrially encoded cytochrome b Homo sapiens