Title : Involvement of prostaglandin receptors (EPR2-4) in in vivo immunosuppression of PGE2 in rat skin transplant model.

Pub. Date : 2005 Jul

PMID : 15914318






2 Functional Relationships(s)
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1 There have been recognized four receptors for PGE2 (EP1-EP4 receptor) so far, and EP2 and EP4 receptors are mainly involved in the immunosuppressive effect of PGE2 in vitro. Dinoprostone prostaglandin E receptor 2 Rattus norvegicus
2 CONCLUSIONS: The effect of PGE2 to prolong the survival of skin transplant requires the action of a combination of three receptors, i.e., EP2+EP3+EP4. Dinoprostone prostaglandin E receptor 2 Rattus norvegicus