Title : Apolipoprotein B mRNA abundance is decreased by eicosapentaenoic acid in CaCo-2 cells. Effect on the synthesis and secretion of apolipoprotein B.

Pub. Date : 1992 Jun

PMID : 1591230






3 Functional Relationships(s)
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1 Pulse-chase experiments were performed to investigate the regulation of apo B synthesis and degradation by the fatty acids. Fatty Acids apolipoprotein B Homo sapiens
2 The inhibition of apo B synthesis by eicosapentaenoic acid may be related to a decrease in gene transcription or a decrease in mRNA stability, as apo B mRNA levels were significantly decreased in cells incubated with this fatty acid. Fatty Acids apolipoprotein B Homo sapiens
3 The inhibition of apo B synthesis by eicosapentaenoic acid may be related to a decrease in gene transcription or a decrease in mRNA stability, as apo B mRNA levels were significantly decreased in cells incubated with this fatty acid. Fatty Acids apolipoprotein B Homo sapiens