Title : Hypertrophic cardiomyopathy: failure to demonstrate mutations in exon 13 of the cardiac beta myosin heavy-chain gene.

Pub. Date : 1992 Mar-Apr

PMID : 1590733






1 Functional Relationships(s)
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1 Amplification of exon 13 of the beta MHC from paraffin-embedded myocardium using the polymerase chain reaction (PCR) was performed and analysis of the amplified product for migration abnormalities using denaturing gradient gel electrophoresis (DGGE) and direct sequencing of the PCR product were used. Paraffin major histocompatibility complex, class I, C Homo sapiens