Title : QM/MM modeling the Ras-GAP catalyzed hydrolysis of guanosine triphosphate.

Pub. Date : 2005 Aug 15

PMID : 15906320






1 Functional Relationships(s)
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1 At the first stage, a unified motion of Arg789 of GAP, Gln61, Thr35 of Ras, and the lytic water molecule results in a substantial spatial separation of the gamma-phosphate group of GTP from the rest of the molecule (GDP). Guanosine Diphosphate RAS p21 protein activator 1 Homo sapiens