Pub. Date : 2005 Jul 15
PMID : 15904896
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The aim of this study was to determine if administration of DHEA might influence adiponectin gene expression and secretion from adipose tissue. | Dehydroepiandrosterone | adiponectin, C1Q and collagen domain containing | Rattus norvegicus |
| 2 | We demonstrate here the inducing effect of exogenously administered DHEA on adiponectin gene expression in epididymal WAT and adiponectin levels in serum of rats fed a DHEA-containing diet (0.6%, w/w) for 2 weeks, accompanied by a reduction in epididymal adipose tissue mass. | Dehydroepiandrosterone | adiponectin, C1Q and collagen domain containing | Rattus norvegicus |
| 3 | We demonstrate here the inducing effect of exogenously administered DHEA on adiponectin gene expression in epididymal WAT and adiponectin levels in serum of rats fed a DHEA-containing diet (0.6%, w/w) for 2 weeks, accompanied by a reduction in epididymal adipose tissue mass. | Dehydroepiandrosterone | adiponectin, C1Q and collagen domain containing | Rattus norvegicus |
| 4 | A corresponding increase in peroxisome proliferator-activated receptor gamma (PPAR(gamma)) mRNA expression suggests that PPAR(gamma) may be involved in the up-regulation of adiponectin gene expression after DHEA treatment. | Dehydroepiandrosterone | adiponectin, C1Q and collagen domain containing | Rattus norvegicus |
| 5 | The presented observations indicate that the positive effects of DHEA, which seems to play a protective role against insulin resistance and atherosclerosis, may be in fact indirect and due to up-regulation of adiponectin gene expression and stimulation of adiponectin secretion from adipose tissue. | Dehydroepiandrosterone | adiponectin, C1Q and collagen domain containing | Rattus norvegicus |
| 6 | The presented observations indicate that the positive effects of DHEA, which seems to play a protective role against insulin resistance and atherosclerosis, may be in fact indirect and due to up-regulation of adiponectin gene expression and stimulation of adiponectin secretion from adipose tissue. | Dehydroepiandrosterone | adiponectin, C1Q and collagen domain containing | Rattus norvegicus |