Title : Akt phosphorylation associates with LOH of PTEN and leads to chemoresistance for gastric cancer.

Pub. Date : 2005 Nov 10

PMID : 15900596






1 Functional Relationships(s)
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1 When the chemotherapeutic sensibilities of these patients were studied in an MTT assay, it was found that the activated AKT was associated with increased resistance to multiple chemotherapeutic agents (5-fluorouracil, adriamycin, mitomycin C and cis-platinum). monooxyethylene trimethylolpropane tristearate AKT serine/threonine kinase 1 Homo sapiens