Title : Subtoxic concentration of doxorubicin enhances TRAIL-induced apoptosis in human prostate cancer cell line LNCaP.

Pub. Date : 2005

PMID : 15897917






6 Functional Relationships(s)
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1 Subtoxic concentration of doxorubicin enhances TRAIL-induced apoptosis in human prostate cancer cell line LNCaP. Doxorubicin TNF superfamily member 10 Homo sapiens
2 In this study, human prostatic cancer cell line LNCaP was found to be resistant to TRAIL-induced apoptosis while it could be restored to TRAIL sensitivity with combination treatment of low concentration of doxorubicin. Doxorubicin TNF superfamily member 10 Homo sapiens
3 In this study, human prostatic cancer cell line LNCaP was found to be resistant to TRAIL-induced apoptosis while it could be restored to TRAIL sensitivity with combination treatment of low concentration of doxorubicin. Doxorubicin TNF superfamily member 10 Homo sapiens
4 TRAIL receptor-1 (DR4) and TRAIL receptor-2 (DR5) were upregulated under the treatment of doxorubicin and verified to be responsible for TRAIL-mediated signal transduction. Doxorubicin TNF superfamily member 10 Homo sapiens
5 TRAIL receptor-1 (DR4) and TRAIL receptor-2 (DR5) were upregulated under the treatment of doxorubicin and verified to be responsible for TRAIL-mediated signal transduction. Doxorubicin TNF superfamily member 10 Homo sapiens
6 Subtoxic concentration of doxorubicin effectively boosted TRAIL sensitivity via depletion of antiapoptotic protein. Doxorubicin TNF superfamily member 10 Homo sapiens