Title : Involvement of PKC and ROS in the cytotoxic mechanism of anti-leukemic decursin and its derivatives and their structure-activity relationship in human K562 erythroleukemia and U937 myeloleukemia cells.

Pub. Date : 2005 Jun 8

PMID : 15896453






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 In the presence of phosphatidylserine (PS), all of 12 compounds 1-12 activated PKC (mainly alpha, beta, and gamma isozymes) but only three compounds 1-3 activated PKC even in the absence of PS. Phosphatidylserines proline rich transmembrane protein 2 Homo sapiens
2 In the presence of phosphatidylserine (PS), all of 12 compounds 1-12 activated PKC (mainly alpha, beta, and gamma isozymes) but only three compounds 1-3 activated PKC even in the absence of PS. Phosphatidylserines proline rich transmembrane protein 2 Homo sapiens