Title : Role of PI3K/Akt and MEK/ERK signaling pathways in sulforaphane- and erucin-induced phase II enzymes and MRP2 transcription, G2/M arrest and cell death in Caco-2 cells.

Pub. Date : 2005 Jun 1

PMID : 15896333






1 Functional Relationships(s)
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1 Erucin (20 microM) induced the mRNAs of NQO1, UGT1A1 and MRP2 by 11.1-, 11.6- and 6.7-fold, whereas sulforaphane (20 microM) induced 3.3-, 5.3- and 2.2-fold, respectively. erucin UDP glucuronosyltransferase family 1 member A1 Homo sapiens