Pub. Date : 1992 May
PMID : 1586993
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | DNA sequence analysis of 1-nitrosopyrene-induced mutations in the hprt gene of Chinese hamster ovary cells. | 1-nitrosopyrene | hypoxanthine-guanine phosphoribosyltransferase | Cricetulus griseus |
| 2 | DNA sequence was determined in 21 mutants induced at the hprt locus of Chinese hamster ovary (CHO) cells by 1-nitrosopyrene, a metabolite of the tumorigenic environmental pollutant 1-nitropyrene. | 1-nitrosopyrene | hypoxanthine-guanine phosphoribosyltransferase | Cricetulus griseus |
| 3 | The results indicate a specificity for the induction of mutations in the hprt gene of CHO cells by 1-nitrosopyrene with respect to both the types of mutations produced and their location in the hprt gene. | 1-nitrosopyrene | hypoxanthine-guanine phosphoribosyltransferase | Cricetulus griseus |
| 4 | The results indicate a specificity for the induction of mutations in the hprt gene of CHO cells by 1-nitrosopyrene with respect to both the types of mutations produced and their location in the hprt gene. | 1-nitrosopyrene | hypoxanthine-guanine phosphoribosyltransferase | Cricetulus griseus |