Title : Sphingosine kinase 1 is involved in dibutyryl cyclic AMP-induced granulocytic differentiation through the upregulation of extracellular signal-regulated kinase, but not p38 MAP kinase, in HL60 cells.

Pub. Date : 2005 Apr 15

PMID : 15863357






5 Functional Relationships(s)
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1 The role of sphingosine kinase (SPHK) in the dibutyryl cyclic AMP (dbcAMP)-induced granulocytic differentiation of HL60 cells was investigated. Bucladesine sphingosine kinase 1 Homo sapiens
2 The role of sphingosine kinase (SPHK) in the dibutyryl cyclic AMP (dbcAMP)-induced granulocytic differentiation of HL60 cells was investigated. Bucladesine sphingosine kinase 1 Homo sapiens
3 The role of sphingosine kinase (SPHK) in the dibutyryl cyclic AMP (dbcAMP)-induced granulocytic differentiation of HL60 cells was investigated. Bucladesine sphingosine kinase 1 Homo sapiens
4 The role of sphingosine kinase (SPHK) in the dibutyryl cyclic AMP (dbcAMP)-induced granulocytic differentiation of HL60 cells was investigated. Bucladesine sphingosine kinase 1 Homo sapiens
5 Pretreatment of HL60 cells with N,N-dimethylsphingosine (DMS), a potent SPHK inhibitor, completely blocked dbcAMP-induced differentiation. Bucladesine sphingosine kinase 1 Homo sapiens