Title : Role of cytosolic NAD(P)H-quinone oxidoreductase and alcohol dehydrogenase in the reduction of p-nitrosophenol following chronic ethanol ingestion.

Pub. Date : 1992 Jun

PMID : 1586150






2 Functional Relationships(s)
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1 In contrast, NADH-dependent C-nitrosoreductase activity was inhibited 70-80% by pyrazole and thus may be attributed mainly to alcohol dehydrogenase(s). NAD aldo-keto reductase family 1 member A1 Rattus norvegicus
2 Increased NADPH-dependent reduction is mediated by the induction of cytosolic NQOR while an NADH-dependent pathway responds to the increased availability of reduced cofactor upon ethanol ingestion and involves mainly the alcohol dehydrogenase-mediated reduction of such compounds. NAD aldo-keto reductase family 1 member A1 Rattus norvegicus