Pub. Date : 2005 Jun 24
PMID : 15843379
13 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | A non-sulfated form of the HNK-1 carbohydrate is expressed in mouse kidney. | Carbohydrates | beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) | Mus musculus |
| 2 | The HNK-1 carbohydrate, which is recognized by anti-HNK-1 antibody, is well known to be expressed predominantly in the nervous system. | Carbohydrates | beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) | Mus musculus |
| 3 | The HNK-1 carbohydrate, which is recognized by anti-HNK-1 antibody, is well known to be expressed predominantly in the nervous system. | Carbohydrates | beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) | Mus musculus |
| 4 | The characteristic structural feature of the HNK-1 carbohydrate is 3-sulfo-glucuronyl residues attached to lactosamine structures (Gal beta1-4GlcNAc) on glycoproteins and glycolipids. | Carbohydrates | beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) | Mus musculus |
| 5 | The biosynthesis of the HNK-1 carbohydrate is regulated mainly by two glucuronyltransferases (GlcAT-P and GlcAT-S) and a sulfotransferase. | Carbohydrates | beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) | Mus musculus |
| 6 | These results suggested that the HNK-1 carbohydrate without sulfate (non-sulfated HNK-1 carbohydrate) is expressed in the kidney. | Carbohydrates | beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) | Mus musculus |
| 7 | These results suggested that the HNK-1 carbohydrate without sulfate (non-sulfated HNK-1 carbohydrate) is expressed in the kidney. | Carbohydrates | beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) | Mus musculus |
| 8 | These results suggested that the HNK-1 carbohydrate without sulfate (non-sulfated HNK-1 carbohydrate) is expressed in the kidney. | Carbohydrates | beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) | Mus musculus |
| 9 | These results suggested that the HNK-1 carbohydrate without sulfate (non-sulfated HNK-1 carbohydrate) is expressed in the kidney. | Carbohydrates | beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) | Mus musculus |
| 10 | We also confirmed the presence of the non-sulfated HNK-1 carbohydrate on N-linked oligosaccharides by multistage tandem mass spectrometry. | Carbohydrates | beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) | Mus musculus |
| 11 | Immunofluorescence staining with antibody M6749 revealed that the non-sulfated HNK-1 carbohydrate was expressed predominantly on the apical membranes of the proximal tubules in the cortex and was also detected in the thin ascending limb in the inner medulla. | Carbohydrates | beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) | Mus musculus |
| 12 | This is the first study indicating the presence of the non-sulfated HNK-1 carbohydrate being synthesized by GlcAT-S in the kidney. | Carbohydrates | beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) | Mus musculus |
| 13 | The results presented here constitute novel knowledge concerning the function of the HNK-1 carbohydrate. | Carbohydrates | beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) | Mus musculus |