Title : Mitochondrial targeting of human O6-methylguanine DNA methyltransferase protects against cell killing by chemotherapeutic alkylating agents.

Pub. Date : 2005 Apr 15

PMID : 15833865






2 Functional Relationships(s)
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1 Furthermore, overexpression of mito-MGMT provided greater resistance to cell killing by 1,3-bis (2-chloroethyl)-1-nitrosourea (BCNU) than overexpression of nucl-MGMT. Carmustine O-6-methylguanine-DNA methyltransferase Homo sapiens
2 Furthermore, overexpression of mito-MGMT provided greater resistance to cell killing by 1,3-bis (2-chloroethyl)-1-nitrosourea (BCNU) than overexpression of nucl-MGMT. Carmustine O-6-methylguanine-DNA methyltransferase Homo sapiens