Title : Are STATS arginine-methylated?

Pub. Date : 2005 Jun 10

PMID : 15826948






1 Functional Relationships(s)
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1 First, we show that treatment of melanoma and fibrosarcoma cells with inhibitors used to suppress methylation (N-methyl-2-deoxyadenosine, adenosine, dl-homocysteine) had profound and rapid effects on phosphorylation of STAT1 and STAT3 but also on p38 and Erk signaling cascades which are known to cross-talk with the Jak/STAT pathway. DL-Homocysteine signal transducer and activator of transcription 1 Homo sapiens