Title : Three emerging new drugs for NSCLC: pemetrexed, bortezomib, and cetuximab.

Pub. Date : 2005 Apr

PMID : 15821248






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Pemetrexed inhibits thymidylate synthase, dihydrofolate reductase, and glycinamide ribonucleotide formyl transferase, enzymes necessary for purine and pyrimidine synthesis, thus causing cell-cycle arrest in the S phase. Pemetrexed dihydrofolate reductase Homo sapiens