Title : Constitutive expression of yeast phospholipid biosynthetic genes by variants of Ino2 activator defective for interaction with Opi1 repressor.

Pub. Date : 2005 May

PMID : 15819625






2 Functional Relationships(s)
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1 Regulated expression of structural genes involved in yeast phospholipid biosynthesis is mediated by inositol/choline-responsive element (ICRE) upstream motifs, bound by the heterodimeric activator complex Ino2 + Ino4. Inositol Ino2p Saccharomyces cerevisiae S288C
2 Gene repression occurs in the presence of sufficient inositol and choline, requiring an intact Opi1 repressor which binds to Ino2. Inositol Ino2p Saccharomyces cerevisiae S288C