Title : A comparison of neurokinin 1 receptor knock-out (NK1-/-) and wildtype mice: exploratory behaviour and extracellular noradrenaline concentration in the cerebral cortex of anaesthetised subjects.

Pub. Date : 2005 Apr

PMID : 15814105






2 Functional Relationships(s)
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1 Here, we have used in vivo microdialysis to compare the concentrations of extracellular noradrenaline ("efflux") in the cerebral cortex of anaesthetised NK1-/- and NK1+/+ mice. Norepinephrine tachykinin 1 Mus musculus
2 Basal noradrenaline efflux was increased 2 to 4-fold in NK1-/- mice compared with NK1+/+ mice but there was no difference in the effects of desipramine. Norepinephrine tachykinin 1 Mus musculus