Title : HSP25 inhibits radiation-induced apoptosis through reduction of PKCdelta-mediated ROS production.

Pub. Date : 2005 May 26

PMID : 15806174






1 Functional Relationships(s)
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1 In the present study, radiation-induced cytochrome c release from mitochondria and activation of caspases accompanied by a decrease of mitochondrial membrane potential in Jurkat T cells were shown to be inhibited by mitochondrial complex I inhibitor rotenone, suggesting that mitochondrial ROS might be important in radiation-induced caspase-dependent apoptosis. ros cytochrome c, somatic Homo sapiens