Title : Fractionation of bovine serum albumin and monoclonal antibody alemtuzumab using carrier phase ultrafiltration.

Pub. Date : 2005 May 5

PMID : 15803473






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1 Using parameter scanning ultrafiltration, the transmission of bovine serum albumin (BSA) and monoclonal antibody alemtuzumab (Campath-1H) through 300 kDa polyethersulfone (PES) ultrafiltration membranes were studied over a range of pH and salt concentrations, with focus on the likely conditions for achieving "reverse selectivity," i.e., obtaining purified alemtuzumab (approximately 155 kDa) in the permeate. polyether sulfone albumin Homo sapiens